What are the side effects for Antabuse?
Common side effects of Antabuse include:
- metallic or garlic-like taste in the mouth,
- skin rash or acne,
- impotence, and.
- swollen or sore tongue.
Who should not take disulfiram?
You should not use disulfiram if you have recently taken metronidazole or paraldehyde, or if you have consumed any foods or products that contain alcohol (mouthwash, cough medicine, cooking wine or vinegar, certain desserts, and others). Do not take disulfiram if you have consumed alcohol within the past 12 hours.
What is the complications of disulfiram?
The adverse effects of disulfiram in the absence of alcohol include nausea, vomiting, drowsiness, halitosis, metallic taste and reduced libido. Dermatitis, hepatitis, peripheral neuritis and encephalopathy may also rarely occur. Disulfiram inhibits dopamine β-hydroxylase and elevates brain concentrations of DA.
What should be avoided when taking Antabuse?
Avoid consuming alcohol while you are taking disulfiram. You should also avoid exposure to alcohol-containing products, such as rubbing alcohol, aftershave, certain mouthwashes, perfumes, hand sanitizers, and some hair sprays.
What is an Antabuse like reaction?
Reviewed on 6/3/2021. Disulfaram-like reaction: a process in the body that produces symptoms similar to those that occur when alcohol is consumed after taking disulfaram (Antabuse). Disulfiram is an oral drug used for treating alcoholism that causes unpleasant symptoms when alcohol is consumed.
How long do Antabuse symptoms last?
These symptoms can last from 30 minutes to several hours. Tell your doctor right away if these symptoms occur, especially if they last or get worse. A more serious reaction with this medication and alcohol may include trouble breathing, seizures, loss of consciousness, chest/jaw/left arm pain.
Can disulfiram cause hepatotoxicity?
The majority of cases of disulfiram hepatotoxicity have been reported from Scandinavian countries. Chronic therapy with disulfiram can cause widespread homogenous eosinophilic inclusions in hepatocytes, similar to the “ground glass” changes that can occur in chronic HBsAg carriers.
Does Antabuse hurt your liver?
This drug may rarely cause serious (rarely fatal) liver disease. If you notice any of the following unlikely but very serious side effects, tell your doctor right away: nausea/vomiting that doesn’t stop, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.
What are symptoms of a disulfiram type reaction?
A disulfiram-like drug is a drug that causes an adverse reaction to alcohol leading to nausea, vomiting, flushing, dizziness, throbbing headache, chest and abdominal discomfort, and general hangover-like symptoms among others.
Can disulfiram cause hypertension?
Disulfiram (DSF) is one of the recommended aids in the management of alcohol dependence. Hypertension may be a clinically significant, dose-dependent, and usually reversible adverse event of DSF therapy.
Does Antabuse make you tired?
Drowsiness, tiredness, headache, acne, and metallic/garlic-like taste in the mouth may occur as your body gets used to the medication. If any of these effects last or get worse, tell your doctor or pharmacist promptly.