What does RNA polymerase II do in transcription?

What does RNA polymerase II do in transcription?

RNA polymerase II (pol II) is a DNA-dependent RNA polymerase that is responsible for transcription of protein-coding genes in the nucleus of eukaryotic cells. Pol II transcription results in synthesis of an RNA copy of the protein-coding DNA strand of genes.

Is RNA polymerase 2 involved in transcription?

RNA polymerase II undergoes extensive co-transcriptional pausing during transcription elongation. This pausing is especially pronounced at nucleosomes, and arises in part through the polymerase entering a transcriptionally incompetent backtracked state.

What is the primary function of polymerase II?

In eukaryotic cells, RNA Polymerase II is responsible for transcribing messenger RNA (mRNA), which is used to make proteins in your cells. It is also responsible for transcribing small nuclear RNA (snRNA) and some microRNA, so it is very important!

How does RNA polymerase II know which genes transcribe?

To begin transcribing a gene, RNA polymerase binds to the DNA of the gene at a region called the promoter. Basically, the promoter tells the polymerase where to “sit down” on the DNA and begin transcribing.

What is the role of RNA polymerase in transcription quizlet?

What is the function of RNA polymerase in transcription? RNA polymerase binds to DNA, separates the strands, then uses one of the strands as a template from which to assemble nucleotides into a complementary RNA strand.

What transcription factors are required by RNA polymerase II?

A minimal RNA polymerase II (pol II) transcription system comprises the polymerase and five general transcription factors (GTFs) TFIIB, -D, -E, -F, and -H. The addition of Mediator enables a response to regulatory factors. The GTFs are required for promoter recognition and the initiation of transcription.

What does RNA polymerase II make quizlet?

RNA polymerase II transcribes polypeptide-coding genes into mRNA.

Which of the following RNA is transcribed by RNA polymerase 2 in eukaryotes?

Protein-coding genes are transcribed by RNA polymerase II to yield mRNAs; ribosomal RNAs (rRNAs) and transfer RNAs (tRNAs) are transcribed by RNA polymerases I and III.

What are the three roles of RNA polymerase in transcription?

It involves copying a gene’s DNA sequence to make an RNA molecule. Transcription is performed by enzymes called RNA polymerases, which link nucleotides to form an RNA strand (using a DNA strand as a template). Transcription has three stages: initiation, elongation, and termination.

What is the main role of RNA polymerase?

RNA polymerase is an enzyme that is responsible for copying a DNA sequence into an RNA sequence, duyring the process of transcription.

Why are interactions between RNA polymerase II and GTFs important for transcription in eukaryotes?

Interactions between RNA polymerase and GTFs increase the rate of transcription because GTFs act as enhancers. RNA polymerase II and GTFs must interact for the polymerase to bind properly at the core promoter site of the DNA.

Which of the following types of RNA are transcribed by RNA polymerase II?

All eukaryotes have three different RNA polymerases (RNAPs) which transcribe different types of genes. RNA polymerase I transcribes rRNA genes, RNA polymerase II transcribes mRNA, miRNA, snRNA, and snoRNA genes, and RNA polymerase III transcribes tRNA and 5S rRNA genes.