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What is EXPAREL used for?
EXPAREL is a medication that helps control your pain after surgery so that you can have a good recovery. EXPAREL is not an opioid or narcotic. It works in your body where you had surgery, unlike opioids, which affect the whole body. During a procedure, the doctor places EXPAREL into the surgical area.
What type of drug is EXPAREL?
Exparel (bupivacaine liposome) is a non-opioid postsurgical analgesic used in the management of postsurgical pain. Exparel provides prolonged postsurgical analgesia for up to 72 hours with a single-dose local administration at the surgical site.
What are the side effects of EXPAREL?
In studies in adults where EXPAREL was injected into a wound, the most common side effects were nausea, constipation, and vomiting. In studies in adults where EXPAREL was injected near a nerve, the most common side effects were nausea, fever, and constipation.
How long does EXPAREL shot last?
In clinical studies, pain relief provided by Exparel lasted from 24 to 72 hours. However, this will vary depending on the type of surgery you have and the dose of Exparel you receive.
Can you mix ropivacaine and EXPAREL?
ropivacaine bupivacaine liposome Therefore, bupivacaine liposome and ropivacaine should not be mixed together or injected into the same area at the same time, as it may cause rapid release of the active medication and alter the safety and efficacy of bupivacaine liposome.
What can you mix EXPAREL with?
DO NOT dilute Exparel with water or other hypotonic agents, as it will result in disruption of the liposomal particles. Use suspensions of Exparel diluted with preservative-free normal (0.9%) saline for injection or lactated Ringer’s solution within 4 hours of preparation in a syringe.
What is the onset of EXPAREL?
The onset of Exparel is rapid. The duration of action is up to 72 hours, however systemic plasma levels can persist for 96 hours after administered locally, and 120 hours after administered into the brachial plexus for an interscalene nerve block.
Is EXPAREL FDA approved?
With this approval, EXPAREL is the first and only FDA approved long-acting local analgesic for the pediatric population as young as age six.
How long has EXPAREL been on the market?
The company’s long-acting local analgesic, EXPAREL® (bupivacaine liposome injectable suspension) was commercially launched in the United States in April 2012.
Is EXPAREL a nerve block?
Exparel is intended for use as a nerve block to relieve pain associated with shoulder surgery for a period of 48 to 72 hours following administration.
What is the drug Marcaine?
Marcaine (bupivacaine hydrochloride) Injection is an anesthetic (numbing medicine) used as a local (in one area) anesthetic for a spinal block. Marcaine is available in generic form.
Can you mix EXPAREL with Marcaine with EPI?
No interactions were found between epinephrine and Exparel.