What is segmental pigmentation disorder?

What is segmental pigmentation disorder?

Segmental pigmentation disorder (SegPD) is a rare type of cutaneous dyspigmentation. This hereditary disorder, first described some 20 years ago, is characterized by hypo and hyperpigmented patches on the trunk, extremities and less likely on the face and neck.

What are 3 common skin pigmentations?

Common types of pigmentation

  • Freckles. The most common type of pigmentation is ephelides, or freckles.
  • Solar lentigines. Also referred to as liver spots or sun spots, these are pigmented spots with a clearly defined edge.
  • Melasma.
  • Post-inflammatory hyperpigmentation.

What can cause hypopigmentation?

The condition most commonly develops as a result of injury or trauma to the skin. Blisters, burns, and infections can all damage the skin and lead to hypopigmentation. Cosmetic skin treatments, such as chemical and laser peels, may also cause hypopigmentation if the procedure is done incorrectly.

Does pigmentary mosaicism go away?

Pigmentary mosaicism is a permanent color change in the skin. We are not able to change the genetic material to make the skin color the same.

What causes a Macule?

Macules can be caused by various conditions that affect the appearance of your skin, resulting in areas of discoloration. Conditions that are likely to cause macules are: vitiligo. moles.

Does hypopigmentation ever go away?

It is important to realize that this is not a permanent lightening of the skin but it resolves slowly. In most cases it takes many months or possibly even a year to go away completely. Since post inflammatory hypopigmentation is a temporary problem usually no treatment is required.

What are the different pigmentations?

Did you know there are actually various types of pigmentation? Freckles, Solar Lentigines, Melasma, Post-Inflammatory Hyperpigmentation and Hypopigmentation are not all synonymous with each other.

What are melanocytes?

(meh-LAN-oh-site) A cell in the skin and eyes that produces and contains the pigment called melanin. Enlarge. Anatomy of the skin, showing the epidermis, dermis, and subcutaneous tissue. Melanocytes are in the layer of basal cells at the deepest part of the epidermis.

Will hypopigmentation go away?

What does hypopigmentation look like?

Hypopigmentation can affect a small area of the skin, or it can be widespread. It usually appears as lighter than normal colored patches on the skin or as areas on the skin that appear white. Hypopigmentation may be caused by injury, inflammation, or infection of the skin.

Is pigmentary mosaicism common?

Most frequently, pigmentary mosaicism appears sporadically, but a family history of the condition was described in 4% of the reported cases. A rare case of two paternal half-brothers with pigmentary mosaicism of the hyperpigmented type was reported [26].

What causes pigmentary mosaicism?

Pigmentary mosaicism is nowadays recognized as a pigmentary disorder caused by somatic chromosomal abnormalities disrupting or accelerating the function of pigmentary genes. Affected individuals with pigmentary mosaicism commonly have multiple congenital abnormalities, developmental delays and/or mental retardation.